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A Study Of The Low Level Radiation Effect on The Mitotic Index of The Basal Cells in The Buccal Pouch Of Hamsters

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Abstract

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¿©ÇÏ°í, ±¸³» ¹æ»ç¼±»çÁø ÃÔ¿µ±â(GX-770, Gendex CorP, Illinois, U.S.A.)·Î 70 kVp, 7 mA,
32 impulseÀÇ Á¶°Ç¿¡¼­ ¾à 30ºÐ µ¿¾È 42ȸ ÃÑ 5460 mRÀ» ÇܽºÅÍ ÇùÃø¿¡ Á¶»çÇÏ°í Á¶»çÁ¾
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1. ´ëÁ¶±ºÀÇ ±âÀú¼¼Æ÷ 26,852°³Áß À¯»çºÐ¿­ÁßÀÎ ¼¼Æ÷¼ö´Â 105°³¿´°í °¢ Ç¥º»ÀÇ ¼¼Æ÷ºÐ¿­Áö
¼ö Æò±Õ°ªÀº 4.32¿´´Ù.
2. ¹æ»ç¼±À» Á¶»çÇÑ ½ÇÇ豺ÀÇ ±âÀú¼¼Æ÷ 25,423°³ Áß À¯»çºÐ¿­ÁßÀÎ ¼¼Æ÷¼ö´Â 59°³¿´°í, °¢
Ç¥º»ÀÇ ¼¼Æ÷ºÐ¿­Ä¡¼ö Æò±Õ°ªÀº 2.46 À̾ú´Ù.
3. ´ëÁ¶±º°ú ½ÇÇ豺ÀÇ ¼¼Æ÷ºÐ¿­Áö¼ö Æò±ÕÄ¡¸¦ t- °ËÁ¤ÇÑ °á°ú(¥á=0.05, ÀÚÀ¯µµ 64,
t=3.44>1.96) Àú¼±·®¹æ»ç¼± Á¶»ç 2½Ã°£ ÈÄ¿¡ ¼¼Æ÷ºÐ¿­Áö¼ö°¡ °¨¼ÒµÊÀ» ¾Ë ¼ö ÀÖ¾ú´Ù.
#ÃÊ·Ï#
The purpose of this study was to investigate the effects of the low level irradiation
on the mitotic index of the basal cells in the buccal pouch of hamsters(golden hamster:
APG strain).
After colchicine was administrated to the hamsters through the intraperitoneal, the low
level radiation(5460mR) was exposed on the buccal pouch of hamsters. The mitotic
index of the basal cells was estimated 2 hours after radiation.
The results were as follows:
1. The mean mitotic index of the control group was 4.32.
2. The mean mitotic index of the irradiated group was 2.46.
3.7-test of data in the irradiated group showed significant difference from the mitotic
index in the control group. These results suggested the lowered mitotic index of the
irradiated group resulted from the low level irradiation.

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